The multicenter real-world report of the efficacies of 14-day esomeprazole-based and rabeprazole-based high-dose dual therapy in first-line Helicobacter pylori eradication in Taiwan

• DOI: 10.1016/j.jmii.2024.02.009
• Publication Date: 2024-03-04T07:26:31Z
• Authors: Wei-Chen Tai; I-Ting Wu; Hsin-Ming Wang; Pao-Yuan Huang; Chih-Chien Yao; Cheng-Kun Wu; Shih-Cheng Yang; Chih-Ming Liang; Pin-I Hsu; Seng-Kee Chuah
• Keywords: Rabeprazole; Esomeprazole

High-dose dual therapy (HDDT) using proton-pump inhibitors (PPI) and amoxicillin attracted attention for its simplicity lower adverse event profile. Besides, vonoprazan is not available worldwide. This real-world study aims to compare the efficacy of esomeprazole-based rabeprazole-based HDDT regimens identify clinical factors influencing outcomes.