How low can we go? The effect of acquisition duration on cardiac volume and function measurements in free-running cardiac and respiratory motion-resolved five-dimensional whole-heart cine magnetic resonance imaging at 1.5T

• DOI: 10.1016/j.jocmr.2025.101863
• Publication Date: 2025-02-14T18:00:51Z
• Authors: Robert J. Holtackers; Augustin C. Ogier; Ludovica Romanin; Estelle Tenisch; Isabel Montón Que...; Ruud B. van Heeswijk; Christopher W. Roy; Jérôme Yerly; Milan Prsa; Matthias Stuber
• Keywords: Angiology

Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac volumes and function using 2D breath-held cine imaging. This technique, however, requires a reliable ECG signal, repetitive breath-holds, time-consuming proficiency-demanding planning of views. Recently, free-running framework has been developed respiratory motion-resolved 5D whole-heart imaging without need an meticulous plan scanning. In this study, we investigate impact acquisition time on volumetric functional measurements, when imaging, compared to reference Sixteen healthy adult volunteers underwent CMR at 1.5T, including durations ranging from 1 6min in randomized order. All datasets were anonymized analysed left-ventricular end-systolic end-diastolic volumes, as well ejection fraction. subset data, intra- inter-observer agreement was assessed. addition, image quality observer confidence scored 4-point Likert scale. Finally, efficiency reported both techniques, which defined required data sampling divided by total scan time. No significant differences EDV ESV found between 1, 2, 3, 5, 6minutes Biases ranged -2.4 -7.4mL, while biases -3.8 2.1mL. fraction any duration -2.8% 0.94%. Both improved increased. However, they always lower than Acquisition 13% 50% or higher Free-running with short one minute can provide comparable albeit expense confidence.