Clinical and psychological factors associated with interdose opioid withdrawal in chronic pain population

• DOI: 10.1016/j.jsat.2021.108386
• Publication Date: 2021-04-08T16:45:52Z
• Authors: Sara Rodríguez-Es...; Ainhoa Coloma-Car...; Ana Pérez-Carbonell; José F. Román-Quiles; José L. Carballo
• Keywords: Depression; Cross-sectional study; Drug withdrawal

The DSM-5 diagnostic criteria for Prescription Opioid-Use Disorder (POUD) have undergone some significant changes. One of the most controversial changes has been elimination withdrawal symptoms criterion when opioid use is under appropriate medical supervision. For this reason, goal study was to analyze factors associated with in patients chronic non-cancer pain (CNCP).This cross-sectional descriptive involved 404 who prescription opioids long-term treatment (≥90 days) CNCP. Measures included sociodemographic and clinical characteristics, POUD, symptoms, craving, anxiety-depressive intensity interference.Forty-seven percent (n = 193) sample reported moderate-severe which were lower age, higher daily morphine dose duration opioids, psychotropic drugs, greater interference (p < .05). Binary logistic regression analysis showed that POUD (OR 2.82), anxiety 2.21), depression 1.81), 1.05), longer strongest .05).Psychological seem play a key role severity symptoms. Since these increases risk developing knowing may be useful preventive psychological interventions.