Hypertension Defined by 2017 ACC/AHA Guideline, Ideal Cardiovascular Health Metrics, and Risk of Cardiovascular Disease: A Nationwide Prospective Cohort Study

• DOI: 10.1016/j.lanwpc.2021.100350
• Publication Date: 2022-01-08T10:06:09Z
• Authors: Shujing Wu; Yu Xu; Ruizhi Zheng; Jieli Lu; Mian Li; Li Chen; Yanan Huo; Min Xu; Tiange Wang; Zhiyun Zhao; Shuangyuan Wang; Hong Lin; Meng Dai; Di Zhang; Jingya Niu; Guijun Qin; Li Yan; Qin Wan; Lulu Chen; Lixin Shi; Ruying Hu; Xulei Tang; Qing Su; Xuefeng Yu; Yingfen Qin; Gang Chen; Zhengnan Gao; Guixia Wang; Feixia Shen; Zuojie Luo; Yuhong Chen; Yinfei Zhang; Chao Liu; Youmin Wang; Shengli Wu; Tao Yang; Qiang Li; Yiming Mu; Jiajun Zhao; Yufang Bi; Weiqing Wang; Guang Ning
• Keywords: Stroke; Guideline

The updated definition of hypertension by the American College Cardiology (ACC) and Heart Association (AHA) is an important paradigm shift has lead to extensive discussion. We aimed examine association between blood pressure (BP) categories risk cardiovascular diseases (CVDs) with potential modifications from other health metrics (CVHMs).This prospective study included 91,204 participants ≥40 years recruited 20 community sites across mainland China. Participants were followed up during 2010-2016 for CVD events including nonfatal myocardial infarction, stroke, heart failure, death. BP defined according 2017 ACC/AHA guideline CVHMs smoking, physical activity, diet, body-mass index, total cholesterol, fasting glucose.Overall, 1,985 major occurred a mean follow-up 3.7 years. Having more ideal significantly reduced in both stage 1 2 hypertension. Compared without hypertension, having ≥4 no longer associated increased (HR=1·04; 95% CI=0·83-1·31), but less so (HR=1·90, CI=1·70-2·13). Such pattern was evident aged <60 (P interaction <0·05).Stage identifies individuals at risk, which can be attenuated achieving preferable health, especially adults