Incidence of post-stroke cognitive impairment in patients with first-ever ischemic stroke: a multicenter cross-sectional study in China

• DOI: 10.1016/j.lanwpc.2023.100687
• Publication Date: 2023-01-14T20:12:17Z
• Authors: Aini He; Zu Wang; Xiao Wu; Wei Sun; Kun Yang; Wuwei Feng; Yuan Wang; Haiqing Song
• Keywords: Stroke; Cross-sectional study; Sequela

Post-stroke cognitive impairment (PSCI) is a common sequela after stroke. China has large population of stroke survivors, but large-scale survey on the incidence and risk factors for PSCI not been undertaken. We aimed to calculate vascular symptoms among first-ever survivors in through multicenter cross-sectional study.From May 1, 2019 November 30, 2019, patients with clinical diagnosis ischemic were recruited from 563 hospitalized-based center networks 30 provinces China. Cognitive was measured by 5-min National Institute Neurological Disease Stroke-Canadian Stroke Network (NINDS-CSN) at 3-6 months indexed Stepwise multivariate regression stratified analysis performed assess association between demographic variables.A total 24,055 enrolled, an average age 70.25 ± 9.88 years. The as per NINDS-CSN 78.7%. Age ≥75 years old (OR: 1.887, 95%CI: 1.391-2.559), western regional residence 1.620, 1.411-1.860) lower education level associated increased risk. Hypertension might be related non-PSCI 0.832, 0.779-0.888). For under 45 old, unemployment independent factor 6.097, 1.385-26.830). who residents southern region 1.490, 1.185-1.873) non-manual workers 2.122, 1.188-3.792), diabetes PSCI.PSCI Chinese stroke, many are occurrence PSCI.The Beijing Hospitals Authority Youth Program (No. QMS20200801); Natural Science Foundation 81801142); Key Project Technology Development Railway Corporation K2019Z005); Capital Health Research Special 2020-2-2014); Innovation 2030-Major 2021ZD0201806).