Magnetic covalent organic framework for effective solid-phase extraction and HPLC determination of ochratoxin A in food

• DOI: 10.1016/j.lwt.2023.114639
• Publication Date: 2023-03-06T10:29:02Z
• Authors: Xiao-Shuai Yang; Jie Zhao; Tian-Tian Ma; Zi-Yu Li; Lu-Liang Wang; Shi-Lei Ji; Meng-Yue Sun; Yu-Shen Liu; Zhen-Hua Hu; Quan-Wen Liu; Cheng-Wu Jin; Shu-Yang Sun; Han-Sheng Gong
• Keywords: Solid phase extraction

Ochratoxin A (OTA) exposure in food poses great threat to human health. Magnetic solid phase extraction (MSPE) is an effective sample pre-treatment method based on liquid chromatographic analysis monitor OTA food. Herein, magnetic covalent organic frameworks (Fe3O4@COFs) nanospheres were prepared and well characterized. The efficient selective of relied large specific surface inherent porosity COFs the hydrogen bonding, π-π hydrophobic interactions between COF shell OTA. MSPE parameters investigated detail. Under optimal conditions, developed Fe3O4@DhaTab-based-MSPE-HPLC-FLD for displayed good linearity (0.1-800 μg L−1) with R2 (0.996) low limit detection (0.03 L−1). proposed was applied determine beer, Chinese Baijiu vinegar satisfactory recoveries (72–111%) relative standard deviations (0.2 5.5%).