Metal-organic framework nanosheets that exhibit pH-controlled drug release

• DOI: 10.1016/j.matlet.2017.02.082
• Publication Date: 2017-02-23T00:18:35Z
• Authors: Xuechuan Gao; Ruixue Cui; Ming Zhang; Zhiliang Liu
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract Crystalline metal–organic framework (MOF) nanosheets have been fabricated from a new bulk MOF (1) which is assembled by ZnII metal ions as nodes and the drug ibuprofen as ligand. Surfactant-assisted synthetic method was used to control the growth of bulk MOF to obtain MOF nanosheets and the obtained MOF nanosheets exhibit good biodegradability and pH-controlled ibuprofen release.