Relación entre infarto de miocardio y ritmo circadiano en pacientes atendidos por un servicio de emergencias prehospitalario

• DOI: 10.1016/j.medcli.2011.09.035
• Publication Date: 2011-12-28T00:58:47Z
• Authors: María Cristina Ba...; José Ramón Garmen...; Julio Ardura Fern...; Juan Pablo Casase...; Jesús María André...; Ervigio Corral To...
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

A B S T R A C T Background and objectives: The aim of this study is to analyze the presence of circadian rhythm in the time of onset of symptoms of acute myocardial infarction treated by a prehospital emergency system and the influence of modifiable cardiovascular risk factors and non-modifiable as modulators of that circadian rhythm. Patients and methods: Retrospective analysis of 709 patients clinically diagnosed with acute myocardial infarction on-site in the prehospital setting. The variables were time to onset of symptoms, age, sex, previous ischemic heart disease, hypertension, diabetes mellitus, hyperlipidemia and smoking. We analyzed the rhythm with cosinor multiple sinusoid method, with 3 harmonics (24, 12 and 8 h) for the