One-pot synthesis of highly substituted imidazoles using molecular iodine: A versatile catalyst

• DOI: 10.1016/j.molcata.2006.10.009
• Publication Date: 2006-10-15T11:37:09Z
• Authors: Mazaahir Kidwai; Poonam Mothsra; Vikas Bansal; Rishi K. Somvanshi; Abdul S. Ethayath...; Sharmistha Dey; Tej P. Singh
• Keywords: 01 natural sciences; 0104 chemical sciences

Molecular iodine has been used an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra substituted imidazoles in excellent yields. The significant features of the iodine-catalyzed condensation are operational simplicity, inexpensive reagents, high yield of products and the use of non-toxic reagents.