An Interactive Database for the Assessment of Histone Antibody Specificity

• DOI: 10.1016/j.molcel.2015.06.022
• Publication Date: 2015-07-23T15:45:40Z
• Authors: Scott B. Rothbart; Bradley M. Dickson; Jesse R. Raab; Adrian T. Grzybowski; Krzysztof Krajewski; Angela H. Guo; Erin K. Shanle; Steven Z. Josefowicz; Stephen M. Fuchs; C. David Allis; Terry R. Magnuson; Alexander J. Ruth...; Brian D. Strahl
• Keywords: Antibody microarray

Access to high quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut The Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloguing the behavior of widely used commercially available histone antibodies by peptide microarray. This interactive web portal provides a critical resource to the biological research community who routinely use these antibodies as detection reagents for a wide range of applications.