Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice

• DOI: 10.1016/j.molmet.2023.101749
• Publication Date: 2023-06-02T02:24:40Z
• Authors: Laura M. Laiglesia; Xavier Escoté; Neira Sáinz; Elisa Felix-Soriano; Eva Santamaría; María Collantes; Marta Fernández-G...; Ignacio Colón-Mesa; Leyre Martínez-Fe...; Tania Quesada-López; Sergio Quesada-Vá...; Carlos Rodríguez-...; José M. Arbones-M...; Ángela M. Valverde; J Alfredo Martínez; Jesmond Dalli; Laura Herrero; Silvia Lorente-Ce...; Francesc Villarroya; María J. Moreno-A...
• Keywords: PRDM16; Adipose tissue macrophages

Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation white (WAT) browning.