TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data

• DOI: 10.1016/j.molp.2020.06.009
• Publication Date: 2020-06-23T07:49:16Z
• Authors: Chengjie Chen; Hao Chen; Yi Zhang; Hannah R. Thomas; Margaret H. Frank; Yehua He; Rui Xia
• Keywords: Interface (matter); Application programming interface; Biological data; Data type

AbstractThe rapid development of high-throughput sequencing (HTS) techniques has led biology into the big-data era. Data analyses using various bioinformatics tools rely on programming and command-line environments, which are challenging and time-consuming for most wet-lab biologists. Here, we present TBtools (a Toolkit for Biologists integrating various biological data handling tools), a stand-alone software with a user-friendly interface. The toolkit incorporates over 100 functions, which are designed to meet the increasing demand for big-data analyses, ranging from bulk sequence processing to interactive data visualization. A wide variety of graphs can be prepared in TBtools, with a new plotting engine (“JIGplot”) developed to maximum their interactive ability, which allows quick point-and-click modification to almost every graphic feature.TBtools is a platform-independent software that can be run under all operating systems with Java Runtime Environment 1.6 or newer. It is freely available to non-commercial users at https://github.com/CJ-Chen/TBtools/releases.