Berberine and coptisine free bases

• DOI: 10.1016/j.molstruc.2003.09.018
• Publication Date: 2003-11-05T17:01:43Z
• Authors: Jiřı́ Dostál; Stanislav Man; Pavlı́na Sečkářová; Dagmar Hulová; Marek Nečas; Milan Potáček; Jaromı́r Toušek; Roger Dommisse; Walter Van Dongen; Radek Marek
• Keywords: Coptisine

Abstract The free bases of protoberberine alkaloids berberine and coptisine and related compounds have been examined. The 1H and 13C NMR data of 8-hydroxy-7,8-dihydroberberine (2a), 8-hydroxy-7,8-dihydrocoptisine (2b), bis(7,8-dihydroberberin-8-yl) ether (3a), 8-oxoberberine (5a), and 8-oxocoptisine (5b) as well as X-ray data of compounds 2a, 5a, and 5b are reported and discussed.