Application of silver oxide nanoparticles for the treatment of cancer

• DOI: 10.1016/j.molstruc.2019.04.041
• Publication Date: 2019-04-10T06:32:00Z
• Authors: Seemab Iqbal; Muhammad Fakhar-e...; Fozia Akbar; M. Shafiq; M. Atif; N. Amin; Muhammad Ismail; Atif Hanif; W. Aslam Farooq
• Keywords: Silver nanoparticle; Silver oxide

Abstract Silver oxide nanoparticles are wonderful material and having great potential towards biomedical applications. Silver oxide nanoparticle were synthesized via Chemical Aqueous method and characterized by applying manifold available techniques. X-ray diffraction (XRD) was used for analyzing structural property of nanoparticle crystals, the morphology of synthesized nanoparticles was studied by scanning electron microscope (SEM), elemental analysis of the composition was observed by energy dispersive X-ray spectra (EDXS) and the optical properties was analyzed by the Uv–Vis spectrometer. Spectroscopic analysis confirmed the spherical morphology of the nanoparticles with the effect of calcined temperature. Phototoxic and cytotoxic effects of grown particles were examined by conducting various relevant experimental techniques on hepatocellular (HepG2 Cell line) model. The obtained results were verified by applying polynomial fit which confirmed the goodness of fit. Silver oxide NPs has unique bio interaction characteristics and physicochemical properties as anticancer agent. This research will be beneficial particularly for cancer therapeutics.