Synthesis, characterization and Al3+ sensing application of a new chromo-fluorogenic chemosensor

• DOI: 10.1016/j.molstruc.2019.05.032
• Publication Date: 2019-05-12T15:28:26Z
• Authors: Xin Leng; Xu Jia; Chengfang Qiao; Wenfeng Xu; Chongting Ren; Ying Long; Bingqin Yang
• Keywords: Salicylaldehyde; Naked eye; Rhodamine; Proton NMR; Rhodamine B

Abstract A rhodamine B-based chromo-fluorogenic probe BOS is prepared with a good yield by condensating an o-diaminobenzene functionalized rhodamine derivative (RBO) and a large steric hindrance salicylaldehyde, and characterized by elemental analysis, infrared spectroscopy (IR), 1H and 13C NMR technology, and high resolution mass spectrum (HRMS). Spectroscopy experiments reveal that the probe can selectively and sensitively detect Al3+ from a variety of metal ions with a low detection limit of 1.855 μmol/L. Compared to traditional detection methods, BOS provides an inexpensive, rapid and straightforward way for Al3+ detection that can be distinguished by “naked eye”. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2-H- tetrazoliubromide) assays and cell imaging experiments demonstrate that the sensor is low toxic and amicable for Al3+ sensing in living cells.