Prevalence of Latent Tuberculosis Infection in Multiple Sclerosis Patients from an Endemic Country: A Cross-Sectional Study

• DOI: 10.1016/j.msard.2025.106354
• Publication Date: 2025-03-01T08:05:59Z
• Authors: Simón Cárdenas-Ro...; Juan Camilo Carri...; María Isabel Zuluaga; Jairo Quiñones-Ba...; Valeria Valencia-...; Erika Paola Verga...; Cristian Eduardo ...; Lorena López-Reyes; Laura Estefanía A...
• Keywords: Cross-sectional study; Endemic diseases

MS patients are at increased risk for tuberculosis reactivation due to immunosuppressive therapies. Prevalence of latent in from our country is unknown. To assess the prevalence and determinants infection (LTBI) Colombia. Multicentric, cross-sectional, retrospective study involving confirmed patients. LTBI was defined as a positive tuberculin skin test asymptomatic with normal chest imaging. The (95 %CI) estimated compared general one-sample proportion test. Determinants were analysed using adjusted logistic regression. 481 included, mean age 42 years duration 10 years. 6.24 % %CI: 4.25-8.78), significantly lower than that population (21.11 %; p < 0.001). Male sex (OR: 2.52; 95 1.00-6.28, = 0.046) independently associated LTBI. less prevalent among sample population, male sex.