Modulation of poly (d,l-lactic acid) with amniotic fluid for improvement of the cell affinity

• DOI: 10.1016/j.msec.2005.03.004
• Publication Date: 2005-06-10T15:46:32Z
• Authors: Yuji Yin; Kaiyong Cai; Xiangshi Li; Kangde Yao; Zhiming Yang; Xiuqiong Li; Huiqi Xie
• Keywords: Modulation (music)

Abstract The objective of this study was to investigate the effects of naturally occurring amniotic fluid modified poly( d,l -lactic acid) (PDLLA) film on the culture of rat calvaria osteoblast. The characteristics of surfaces (both modified and control) were examined by contact angle measurement and electron spectroscopy for chemical analysis (XPS). Cell adhesion and proliferation were used to assess the cell behavior on modified films and control one. MTT assay was used to determine cell viability and alkaline phosphatase (ALP) activity was taken to evaluate differentiated cell function. Compared with the untreated films, cell adhesion of osteoblast was significantly higher ( P P P P