Predictors of pain reduction following a program of manual therapies for patients with temporomandibular disorders: A prospective observational study

• DOI: 10.1016/j.msksp.2022.102634
• Publication Date: 2022-07-31T14:31:31Z
• Authors: Giacomo Asquini; Valter Devecchi; Giulia Borromeo; Domenico Viscuso; Federico Morato; Matteo Locatelli; Deborah Falla
• Keywords: Nomogram; Explained variation

Clinical guidelines recommend conservative treatment for the management of temporomandibular disorders (TMD), and manual therapy (MT) is commonly applied to reduce pain improve function. To identify predictors reduction functional improvement following a program therapies (MTP) in patients with TMD develop first screening tool that could be used clinical practice facilitate decision-making. A cohort 102 adults diagnosis were treated four weekly sessions within MTP craniomandibular structures. Candidate demographic variables, general health psychosocial features, characteristics related tests. intensity by at least 30% after was considered good outcome. Logistic regression adopted predictive model its performance assessed considering explained variance, calibration, discrimination. Internal validation prediction models further evaluated 500 bootstrapped samples. Patients experiencing greater than 2/10 during mouth opening, positive expectations outcome MTP, localized craniocervical region, low Central Sensitization Inventory score obtained MTP. Predictive identified physical psychological variables characterized high variance (R2 = 58%) discrimination (AUC 89%) internal validation. preliminary developed presented as nomogram. The revealed promising findings, although these need externally validated future research. NCT03990662.