Posterior insula repetitive transcranial magnetic stimulation for chronic pain in patients with Parkinson disease – pain type matters: A double-blinded randomized sham-controlled trial

• DOI: 10.1016/j.neucli.2024.102994
• Publication Date: 2024-07-17T12:46:15Z
• Authors: Victor Rossetto B...; Gabriel Taricani ...; Valquíria Apareci...; Luciana Mendonça ...; Debora Arnaut; Antônia Lilian de...; Ricardo Galhardoni; Egberto Reis Barbosa; Andre Russowsky B...; Manoel Jacobsen T...; Rubens Gisbert Cury; Daniel Ciampi de ...
• Keywords: Male; Adult; Non-motor symptoms, nociceptive pain; Insula; Chronic pain; Parkinson Disease; Middle Aged; Transcranial Magnetic Stimulation; Parkinson disease; Treatment Outcome; Double-Blind Method; Humans; Pain Management; Female; Insular Cortex; Chronic Pain; Transcranial magnetic stimulation; Aged

Altered somatosensory processing in the posterior insula may play a role chronic pain development and contribute to Parkinson disease (PD)-related pain. Posterior-superior (PSI) repetitive transcranial magnetic stimulation (rTMS) has been demonstrated have analgesic effects among patients with some conditions. This study aimed at assessing efficacy of PSI-rTMS for treating PD-related