Functional representation of the finger and face in the human somatosensory cortex: intraoperative intrinsic optical imaging

• DOI: 10.1016/j.neuroimage.2004.12.049
• Publication Date: 2005-02-18T12:50:59Z
• Authors: Katsushige Sato; Tadashi Nariai; Yoji Tanaka; Taketoshi Maehara; Naohisa Miyakawa; Shinichi Sasaki; Yoko Momose-Sato; Kikuo Ohno
• Keywords: Adult; Male; 0301 basic medicine; Brain Neoplasms; Somatosensory Cortex; Middle Aged; Electric Stimulation; Neurosurgical Procedures; Fingers; 03 medical and health sciences; Face; Monitoring, Intraoperative; Image Processing, Computer-Assisted; Humans; Female; Peripheral Nerves; Trigeminal Nerve; Nerve Net; Aged

We applied the intrinsic optical imaging technique to the human primary somatosensory cortex during brain tumor/epilepsy surgery for nine patients. The cortical surface was illuminated with a Xenon light through an operating microscope, and the reflected light, which passed through a 605 nm bandpass filter, was detected by a CCD camera-based optical imaging system. Individual electrical stimulation of five digits induced changes in the reflected light intensities. Visualizing the intrinsic optical responses, we constructed maps of finger representation in Brodmann's area 1. In the maps, response areas of Digits I to V were sequentially aligned along the central sulcus in the crown of the postcentral gyrus from the latero-inferior region (Digit I) to the medio-superior region (Digit V). The neighboring response areas partially overlapped each other, as previously described in the monkey somatosensory cortex. Similar results were obtained in the face region with stimulation of the three branches of the trigeminal nerve. These results suggest that the overlap of the response areas is a common feature in the somatosensory cortex not only in monkeys, but also in humans.