Advancing Translational Research Using NIMH Research Domain Criteria and Computational Methods

• DOI: 10.1016/j.neuron.2019.02.024
• Publication Date: 2019-03-06T16:02:59Z
• Authors: Charles A. Sanislow; Michele Ferrante; Jennifer Pacheco; Matthew V. Rudorfer; Sarah E. Morris
• Keywords: Research Domain Criteria; Translational Research; Translational Science

The NIMH Research Domain Criteria (RDoC) can aid in the translation of integrative neuroscience. We argue that the RDoC framework, with its emphasis on integration across units of analysis, leveraged with computational approaches, can organize intermediary treatment targets and clinical outcomes, augmenting the translational stream.