Densification of hydroxyapatite through cold sintering process: Role of liquid phase chemistry and physical characteristic of HA powder

• DOI: 10.1016/j.oceram.2024.100566
• Publication Date: 2024-03-02T11:56:24Z
• Authors: Muthusundar Kumar; Mohamed Aymen Ben...; Marie Lasgorceix; Paulo Quadros; Rosica Mincheva; Jean-Marie Raquez; Anne Leriche
• Keywords: Phosphoric acid; Liquid phase; Relative density

Hydroxyapatite is a well-known bioactive material widely employed in bone regeneration applications. Densifying hydroxyapatite at the nanoscale remains challenging with conventional sintering methods. This investigation focuses on densification of commercially available nano-hydroxyapatite powders through cold process, utilizing water, acetic acid, and phosphoric acid solutions as transient liquids under 360 MPa pressure 200 °C. The study systematically examines influence physical parameters powder, liquid nature, ionic concentrations microstructural characteristics. relative density consolidated samples varied respect to concentration solution. Notably, maximum 90% has been achieved for sintered using 2 M solution without changing original phase hydroxyapatite. Overall, this offers valuable insights into impact chemistry technique.