Expert Performance in Visual Differentiation of Bacterial and Fungal Keratitis

• DOI: 10.1016/j.ophtha.2021.09.019
• Publication Date: 2021-10-07T21:05:57Z
• Authors: Travis K. Redd; N. Venkatesh Prajna; Muthiah Srinivasan; Prajna Lalitha; Tiru Krishnan; Revathi Rajaraman; Anitha Venugopal; Brandon Lujan; Nisha Acharya; Gerami D. Seitzman; Jennifer Rose-Nus...; Thomas M. Lietman; J. Peter Campbell; Jeremy D. Keenan; Diana Alvarez-Mel...; Menen Ayalew; Ashwin Balasubram...; Elsie Chan; Matilda Chan; Meenu Chaudhary; Thomas Chia; James Chodosh; Y.Y. Choong; Joseph Christenbury; Josephine Christy; John Clements; John Dart; Mohammad Dastjerdi; Matthew Denny; Sathish Devarajan; Mohamed Elghobaier; Chris Estopinal; Preethika Gandhi; Nikhil Gokhale; Colleen Halfpenny; Rossen Hazarbassanov; Natalie Hernandez; Anna Hovakimyan; David Hwang; Frank Hwang; Tomas Jaeschke; Vishal Jhanji; Faris Karas; Divya Karthik; Camila Kase; Lakshmi Kattana; Tyson Kim; Aaleya Koreishi; David Liang; Christine Martinez; Rafael Martinez-C...; Stephen McLeod; Jodhbir S. Mehta; Michael Mimouni; Adam Moss; Afshan Nanji; Nathan Nataneli; Vasudha Panday; Sayali Pradhan; Ying Qian; Naveen Rao; Julie Schallhorn; Ruti Sella; Suvitha Selvaraj; David Spokes; Neha Shaik; Nakul Shekhawat; Alan Sugar; Audrey Talley Rostov; Napaporn Tananuvat; Chulaluck Tangmon...; Tanya Trinh; Sonal Tuli; Phit Upaphong; Bart van Dooren; Manoj Vasudevan; Elizabeth Viriya; Maria Woodward
• Keywords: Ophthalmological; Eye Infections; Clinical Sciences; Expert Systems; Diagnostic Techniques, Ophthalmological; Ophthalmology & Optometry; Eye Infections, Bacterial; Cornea; Diagnosis, Differential; 03 medical and health sciences; 0302 clinical medicine; Fungal keratitis; Opthalmology and Optometry; Diagnosis; Humans; Corneal Ulcer; Bacteria; Infectious keratitis; Bacterial; Fungi; Diagnostic Techniques; Fungal; ROC Curve; Bacterial keratitis; Area Under Curve; Differential; Public Health and Health Services; Corneal Ulcer Image Interpretation Study Group; Eye Infections, Fungal; Corneal ulcer; Specialization

Abstract: This study quantifies the performance of an international cohort of cornea specialists in image-based differentiation of bacterial and fungal keratitis, identifying significant regional variation and establishing a reference standard for comparison against machine learning models.