Understanding mechanistic aspects and therapeutic potential of natural substances as anticancer agents

• DOI: 10.1016/j.phyplu.2023.100418
• Publication Date: 2023-01-28T03:01:07Z
• Authors: Aakash Deep; Davinder Kumar; Nitin Bansal; Balasubramanian N...; Rakesh Kumar Marwaha; Prabodh Chander S...
• Keywords: Cancer Treatment

Cancer, a diverse class of illnesses that have serious impact on the human population, is severe, complicated challenge in health care delivery and public policy. A healthy lifestyle may help us avoid several types cancer. In 2020, there were 10.3 million cancer deaths 19.3 new cases worldwide. lot anticancer medications been discovered due to extensive screening synthetic compounds natural chemicals over last 50 years. The search for chemotherapeutic agents are more effective, selective, less toxic, unique still underway. Plant-derived drugs potent inhibitors cell lines therefore high demand. exploitation these active ingredients must be managed keep up with demands sustainable. This paper describes various phytoconstituents from plant origin potential. main goal this article increase use products also interest whole world anti-cancer activity compounds. desirable treatment because they readily available. Several useful come plants played an important role list includes Vinblastine, Vincristine, Docetaxel, Etoposide derived Epipodophyllotoxin Paclitaxel (Taxol), Flavonoids, Ginkgo biloba, Curcuma longa, Berberine, etc. However, marine organisms microbiological provided bioactive agents/compounds therapeutic effects Anti-cancer potential alongside herbal products. Examples such trabectedin, dolastin, halichondrin, anthracyclines enediynes. focuses novel research explore activities reported target tumor microenvironment.