Phenylpropanoids from Brachybotrys paridiformis Maxim. ex Oliv. and their anti-HBV activities

• DOI: 10.1016/j.phytochem.2022.113114
• Publication Date: 2022-02-08T23:02:12Z
• Authors: Si-Tong Wu; Yi-Xiao Wang; Bai-Hong Yu; Chun-Liu Ma; He-Qin Qiu; Guang-Shu Wang
• Keywords: Hepatitis B virus; Humans; Biodiversity; Hep G2 Cells; Boraginaceae; Antiviral Agents; 01 natural sciences; Taxonomy; 0104 chemical sciences; 3. Good health

Using chemical and spectroscopic data, this study on Brachybotrys paridiformis Maxim. ex Oliv. identified four undescribed phenylpropanoids, brachin A-C and brachoside A, together with nine other known compounds. The isolated compounds were tested for anti-hepatitis B virus activities in the HepG2.2.15 cell line. Among them, caffeic anhydride showed the most potent activity.