Characterization of antimicrobial resistance in chicken-source phylogroup F Escherichia coli: similar populations and resistance spectrums between E. coli recovered from chicken colibacillosis tissues and retail raw meats in Eastern China

• DOI: 10.1016/j.psj.2021.101370
• Publication Date: 2021-06-30T05:47:16Z
• Authors: Min Wang; Min Jiang; Zhongxing Wang; Rui Chen; Xiangkai Zhuge; Jianjun Dai
• Keywords: Replicon

The extended-spectrum cephalosporin resistant E. coli from food animals transferring to community settings of humans causes a serious threat public health. Unlike phylogroup B2 strains, the clinical significance isolates in F is not well revealed. Here, we report on collection (n = 563) recovered chicken colibacillosis tissues and retail raw meat samples Eastern China. There was an overlapped distribution MLST types between colibacillosis-origin meat-source coli, including dominant STs (ST648, ST405, ST457, ST393, ST1158, etc). This study further investigated presence β-lactamase (ESBL/pAmpC) producers these chicken-source strains. prevalence strains separately accounted for 66.1 71.2%. resistance genotypes plasmid replicon were characterized by multiplex PCR. Our results revealed CTX-M, OXA, CMY TEM genes widespread blaCTX-M most predominant ESBL gene. Moreover, there high non-lactamase β-lactam-resistant isolates. replicons IncB/O/K/Z, IncI1, IncN, IncFIC, IncQ1, IncX4, IncY, p0111, associated with antibiotic-resistant large plasmids, coli. no obvious difference populations, spectrums, meats. detail assessment population genotype showed might hold zoonotic risk contribute spread multidrug-resistant humans.