Suspicion and referral of patients with transthyretin amyloid cardiomyopathy: Recommendations by a Portuguese multidisciplinary expert panel

• DOI: 10.1016/j.repc.2024.12.002
• Publication Date: 2025-02-14T11:11:22Z
• Authors: Dulce Brito; João Agostinho; Carlos Aguiar; Sílvia Aguiar Rosa; Nuno Cardim; Cândida Fonseca; Nuno Marques; Pedro Moraes Sarm...; Patrícia Rodrigues; Jonathan Santos; Maria João Vidiga...; Olga Azevedo
• Keywords: Amiloidose cardíaca; Referenciação; Miocardiopatia por amiloidose de transtirretina; Consenso; Diagnóstico; Algoritmo; RC666-701; Diseases of the circulatory (Cardiovascular) system

Early diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) is crucial for better disease management and outcome. To ensure timely diagnosis, a multidisciplinary panel Portuguese experts, including cardiologists, internal medicine specialists, general practitioners, have developed national consensus to aid physicians in enhancing the referral patients with suspicion ATTR-CM Portugal. A structured approach was used develop consensus: (1) an online survey aimed at identifying clinical red flags, patient journeys, diagnostic tools related ATTR-CM; (2) face-to-face roundtable meeting where findings were discussed reached on algorithms Portugal; (3) critical review proposed algorithms. The Portugal considering current recommendations, but also existence nationwide network specialized clinics reference centers familial polyneuropathy due endemic p.V50M variant. This collaborative effort aims enhance awareness, facilitate referrals improve early ultimately ensuring