Synthesis and characterization of biocompatible hybrid coating on WE54 Mg alloy for implant applications

Biocompatibility Simulated body fluid Biocompatible material
DOI: 10.1016/j.rineng.2024.101784 Publication Date: 2024-02-03T08:37:16Z
ABSTRACT
Magnesium (Mg) and its alloys are prospective biodegradable metallic implant materials. This research focuses on addressing the high corrosion rate of WE54 Mg alloys, limiting their biomedical applications as implants. The study proposes a novel approach by developing hybrid coatings these materials, combining organic PLA (poly-lactic acid) inorganic HA (hydroxyapatite) substances. exhibit significantly improved protection biocompatibility, reducing degradation in vitro rates body fluid solutions. Immersion testing indicates substantial decrease simulated (SBF). Electrochemical studies reveal that HA/PLA coating enhances resistance about 280 times compared to unmodified approximately 230 uncoated alloy. Cytotoxicity tests affirm bioactivity suggesting potential promising solutions for fabricating implants applications.
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