A case report of a lung transplant recipient receiving belatacept in combination with low dose tacrolimus complicated by progressive multifocal leukoencephalopathy

• DOI: 10.1016/j.rmcr.2024.102028
• Publication Date: 2024-04-28T00:46:01Z
• Authors: Vahdatpour C; Saha B; Younis M; Montuoro C; Timofte I; Rackauskas M; Emtiazjoo A
• Keywords: Belatacept; Immunosuppression

Belatacept is a novel T-cell costimulation blockade agent that has unresolved controversy in lung transplant recipients. been recognized as calcineurin sparing for solid organ recipients after reported success renal patients, despite limited evidence other We present the first case of recipient receiving Belatacept, combination with low dose inhibitor, who developed progressive multifocal leukoencephalopathy. While without inhibitor associated increased risk acute rejection recipients, its infectious profile remains unclear.