Incidence and prevalence of systemic lupus erythematosus in urban China, 2013–2017: A nationwide population-based study

• DOI: 10.1016/j.scib.2024.04.075
• Publication Date: 2024-08-12T22:00:38Z
• Authors: Mucong Li; Chaiquan Li; Mengzhuo Cao; Ke Lu; Chanyuan Wu; Jinxi Wang; Chen Wei; Jiuliang Zhao; Qian Wang; Xinping Tian; Xun Tang; Mengtao Li; Xiaofeng Zeng; Pei Gao
• Keywords: Rate ratio

Systemic lupus erythematosus (SLE) is becoming a growing public health concern due to increasing disease and economic burdens. Epidemiological information about SLE, especially its incidence rate, limited in developing countries. In the current study, we sought investigate incidence, prevalence, burdens of SLE urban China. We conducted nationwide population-based cohort study using databases from Urban Employee Basic Medical Insurance Resident between 2013 2017, covering approximately 300 million residents 23 provincial regions Incidence rate prevalence were standardized by age gender China's 2010 national census data. Additionally, calculated average annual costs hospital visit rates. A total 132,258 patients identified during period, with mean 43.03 years (standard deviation: 15.29 years). Of these patients, 81.33% women. China was 14.09 (95% confidence interval (CI), 11.95–16.41) per 100,000 person-years, higher women than men (26.41 vs. 5.92 person-years). Standardized 2017 47.61 (41.77–53.83), 94.16 (80.67–108.69), 17.86 (13.84–22.38) people overall, female, male populations, respectively. The rates increase 21.50%, 19.72%, 25.67% age-specific peaked at 30–49 old 40–59 men. incident prevalent cases most common North-West less southern eastern Distinct variations across different are also consistent varying levels ultraviolet radiation exposure estimated per-capita cost 1599.34 US dollars highest observed adolescent young adult among groups. population rapidly expanding, younger onset, women, which has placed significant on healthcare system.