Application of a novel prioritisation strategy using non-target screening for evaluation of temporal trends (1969–2017) of contaminants of emerging concern (CECs) in archived lynx muscle tissue samples

• DOI: 10.1016/j.scitotenv.2022.153035
• Publication Date: 2022-01-11T01:50:07Z
• Authors: Wiebke Dürig; Nikiforos A. Alyg...; Karin Wiberg; Lutz Ahrens
• Keywords: Univariate; Statistical Analysis

Most environmental monitoring studies of contaminants emerging concern (CECs) focus on aquatic species and target specific classes CECs. Even with wide-scope screening methods, relevant CECs may be missed. In this study, non-target (NTS) was used for tentative identification potential in muscle tissue the terrestrial top predator Eurasian lynx (Lynx lynx). Temporal trend analysis applied as a prioritisation tool archived samples, using univariate statistical tests (Mann-Kendall Spearman rank). Pooled collected from 1969 to 2017 analysed an eight-point time series previously validated workflow. Following peak detection, alignment, blank subtraction, 12,941 features were considered analysis. Prioritisation by time-trend detected 104 61 statistically significant increasing decreasing trends, respectively. probable molecular formula assignment elucidation MetFrag, two compounds one trend, tentatively identified. These results show that, despite low expected concentration levels high matrix effects species, it is possible prioritise samples NTS approaches.