Costs and Outcomes of Acute Kidney Injury in Critically Ill Patients with Cancer

• DOI: 10.1016/j.suponc.2011.03.008
• Publication Date: 2011-07-06T00:22:15Z
• Authors: Amit Lahoti; Joseph L. Nates; Chris D. Wakefield; Kristen J. Price; Abdulla K. Salahu...
• Keywords: Rifle

Acute kidney injury (AKI) is a common complication in critically ill patients with cancer. The RIFLE criteria define three levels of AKI based on the percent increase serum creatinine (Scr) from baseline: risk (> or = 50%), 100%), and failure 200% requiring dialysis). utility cancer not known.To examine incidence, outcomes, costs associated cancer.We retrospectively analyzed all admitted to single-center ICU over 13-month period baseline Scr < 1.5 mg/dL (n 2,398). Kaplan-Meier estimates for survival by category were calculated. Logistic regression was used determine association 60-day mortality. A log-linear model economic analysis. Costs assessed hospital charges provider's perspective.For risk, injury, categories AKI, incidence rates 6%, 2.8%, 3.7%; 62%, 45%, 14%; adjusted odds ratios mortality 2.3, 3, 14.3, respectively (P 0.001 compared without AKI). Hematologic malignancy hematopoietic cell transplant Hospital cost increased 0.16% per 1% 21% dialysis.Retrospective Single-center study. No adjustment cost-to-charge ratios.AKI higher