Polymer-supported selenium-induced electrophilic cyclization: solid-phase synthesis of poly-substituted dihydrofurans and tetrahydrofurans

• DOI: 10.1016/j.tet.2004.08.042
• Publication Date: 2004-09-14T14:27:23Z
• Authors: E. Tang; Xian Huang; Wei-Ming Xu
• Keywords: Solid-Phase Synthesis

Poly-substituted dihydrofurans and tetrahydrofurans have been synthesized through polymer-supported selenium-induced intramolecular electrophilic cyclization, followed by selenoxide syn-elimination or novel nucleophilic substitution cleavage of selenium resin with good yields and purities.