A general, highly enantioselective Michael addition of nitroalkanes to α,β-unsaturated enones catalyzed by 9-amino(9-deoxy)-epi-quinine: a remarkable additive effect

• DOI: 10.1016/j.tet.2016.07.008
• Publication Date: 2016-07-04T16:46:05Z
• Authors: Siyang Liu; Qingqing Wang; Ling Ye; Zhichuan Shi; Zhigang Zhao; Xuejun Yang; Keyi Ding; Xuefeng Li
• Keywords: Michael reaction; Reactivity; Addition reaction; Base (topology)

AbstractThe protocol allows for the transformation of a broad range of enones, such as cinnamone derivatives, cyclic enones and chalcones including heterocyclic derivatives.