Perfluoroalkyl borates and boronic esters: new promising partners for Suzuki and Petasis reactions

• DOI: 10.1016/j.tetlet.2003.09.072
• Publication Date: 2003-10-15T14:37:52Z
• Authors: Alexander A Kolom...; Alexander A Kadyrov; Joanna Szczepkows...; Magdalena Milewska; Henryk Koroniak; German Bissky; Jan A Barten; Gerd-Volker Rösch...
• Keywords: Trimethylsilane; Trifluoromethanesulfonate; Suzuki reaction; Boronic acid

Abstract Lithium and potassium trifluoromethyl-, pentafluoroethyl- and [(diethylphosphinyl)difluoromethyl]trialkoxyborates were synthesized by reaction of either perfluoroalkyllithium or (perfluoroalkyl)trimethylsilane/F − with trialkoxyboranes. Treatment of perfluoroalkyltrialkoxyborates with methanesulfonyl chloride, methyl triflate or methyl tosylate furnished the hitherto unknown trifluoromethyl-, pentafluoroethyl- and [(diethylphosphinyl)difluoromethyl]boronic esters.