Synthesis of nitrocyclopropyl peptidomimetics

• DOI: 10.1016/j.tetlet.2013.09.106
• Publication Date: 2013-09-27T20:30:51Z
• Authors: Norma K. Dunlap; Jacob Basham; Matthew Wright; Katrina Smith; Omar Chapa; Jihun Huang; Will Shelton; Yaroslav Yatsky
• Keywords: 01 natural sciences; 3. Good health; 0104 chemical sciences

Abstract Nitrocyclopropanation of amino-acid derived enones has led to a series of cyclopropyl peptidomimetics suitable for further elaboration to compounds with the potential for biological activity.