A novel straightforward synthesis of 2,4,6-triaryl-1,3,5-triazines via copper-catalyzed cyclization of N-benzylbenzamidines

• DOI: 10.1016/j.tetlet.2014.10.091
• Publication Date: 2014-10-28T19:27:22Z
• Authors: Pradip Debnath; K.C. Majumdar
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract A novel, straightforward method for the synthesis of 2,4,6-triaryl-1,3,5-triazines via copper-catalyzed cyclization of N -benzylbenzamidines in DMSO has been developed. Compared to other methods, the present protocol has a number of advantages such as—cost-effectiveness, avoidance of aldehydes or alcohols as reaction partners, and easy accessibility of starting materials, making it a highly practical approach to access various 2,4,6-triaryl-1,3,5-triazines.