Diastereoselective synthesis of β-aminosulfones from the 1,2-addition to N-(para-methoxyphenyl) imines

• DOI: 10.1016/j.tetlet.2014.11.017
• Publication Date: 2014-11-10T08:15:40Z
• Authors: James C. Anderson; Ian B. Campbell; Sebastien Campos; Jonathan Shannon
• Keywords: Sulfone; Imine; Diastereoselective; Organic Chemistry; Drug Discovery; β-Aminosulfone; Biochemistry; 01 natural sciences; 1,2-addition; 3. Good health; 0104 chemical sciences

AbstractSulfone substituents are found to influence the diastereoselectivity of the 1,2‐addition reaction to imines (II).