Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization

• DOI: 10.1016/j.tetlet.2016.02.094
• Publication Date: 2016-02-28T18:44:37Z
• Authors: François Hallé; Olivier Van der P...; Christelle Doebelin; Marie Niederst; Séverine Schneider; Martine Schmitt; Steven Ballet; Frédéric Bihel
• Keywords: [CHIM.ORGA]Chemical Sciences/Organic chemistry; [CHIM]Chemical Sciences; 01 natural sciences; 0104 chemical sciences

AbstractIntramolecular Buchwald—Hartwig cyclization of 2‐bromophenylalanine derivatives allows the synthesis of chiral dihydroquinolines (II).