A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines

• DOI: 10.1016/j.tetlet.2017.01.061
• Publication Date: 2017-01-21T05:49:23Z
• Authors: Leonid G. Voskres...; Tatiana N. Borisova; Maria D. Matveeva; Viktor N. Khrustalev; Alexander A. Titov; Alexander V. Aksenov; Svetlana V. Dyach...; Alexey V. Varlamov
• Keywords: Activated alkynes; Lamellarin; Pyrrolo[2,1-a]isoquinolines; 540; 01 natural sciences; 0104 chemical sciences

The facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines from the reaction of 1-aroyl-3,4-dihydroisoquinolines and symmetrical alkynes in toluene is described. The novel compounds contain functional groups that are suitable for further modification. © 2017