Opportunities and shortcomings of ionic liquids in single-drop microextraction

• DOI: 10.1016/j.trac.2015.03.024
• Publication Date: 2015-07-16T14:59:25Z
• Authors: Łukasz Marcinkowski; Francisco Pena-Pe...; Adam Kloskowski; Jacek Namieśnik
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract The synergistic combination of ionic liquids (ILs) and single-drop microextraction (SDME) involves a powerful coupling toward the development of sustainable analytical methodologies. This overview provides a survey of the literature regarding IL-SDME, including a database on relevant physicochemical properties of ILs for their application in SDME, the strategies implemented to combine IL-based SDME methods efficiently with analytical instrumentation, and a critical evaluation of the analytical applications involving IL-based SDME methodologies. Overall, this work identifies current inefficiencies, challenges and opportunities of this convenient, yet underexploited, analytical approach.