An Increase in Deceased Donor Incidence Alleviated the Need for Urgent Adult Living Donor Liver Transplantation in a Korean High-Volume Center

• DOI: 10.1016/j.transproceed.2009.12.059
• Publication Date: 2010-06-23T04:32:17Z
• Authors: S. Hwang; S.G. Lee; C.S. Ahn; K.H. Kim; D.B. Moon; T.Y. Ha; G.W. Song; D.H. Jung; K.W. Kim; N.K. Choi; G.C. Park; Y.D. Yu; Y.I. Choi; P.J. Park
• Keywords: Adult; Carcinoma, Hepatocellular; Korea; Adolescent; Waiting Lists; Liver Diseases; Liver Neoplasms; Middle Aged; Tissue Donors; Liver Transplantation; 03 medical and health sciences; 0302 clinical medicine; Cadaver; Living Donors; Hepatectomy; Humans; Retrospective Studies

This study analyzed the effects of a recent increase in deceased donors on the pattern of adult liver transplantation (OLT) in a high-volume center in Korea.OLT patterns relative to pretransplant recipient status were analyzed for 112 deceased donor LTs (DDLT) and 743 living donor OLT (LDLT) in a single center as compared to nationwide Korean data over 3 years from 2006 to 2008.During the study period, the annual proportion of institutional urgent OLT was relatively invariable (20% to 25.2%), but the annual proportion of DDLTs to all OLT increased from 8.9% to 19.9%, as did the annual rate of DDLTs among those undergoing urgent OLT, from 18.6% to 65.8%, with a reciprocal decrease in the proportion of urgent LDLTs. Korean nationwide data also showed a noticeable increase in deceased liver graft allocation for urgency from 39.8% to 62.2% over the same time period.An increase in deceased donors up to 5 per million enabled an increase in urgent adult DDLTs, alleviating the need for urgent adult LDLTs in Korea.