Considerable Risk of Restenosis After Endoscopic Treatment for Hepaticojejunostomy Stricture After Living-Donor Liver Transplantation

• DOI: 10.1016/j.transproceed.2015.09.015
• Publication Date: 2015-10-27T10:20:31Z
• Authors: H. Kamei; H. Imai; Y. Onishi; M. Ishihara; M. Nakamura; H. Kawashima; M. Ishigami; A. Ito; N. Ohmiya; Y. Hirooka; H. Goto; Y. Ogura
• Keywords: Adult; Male; Adolescent; Anastomosis, Surgical; Jejunostomy; Constriction, Pathologic; Middle Aged; Liver Transplantation; 3. Good health; Biliary Tract Surgical Procedures; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Liver; Recurrence; Living Donors; Hepatectomy; Humans; Female; Endoscopy, Digestive System; Cholangiography; Aged

There are few reports on the short- and long-term follow-up of endoscopic retrograde cholangiography (ERC) in adult patients with hepaticojejunostomy (HJS) stricture after living-donor liver transplantation (LDLT).Nine LDLT recipients underwent ERC with the use of double-balloon endoscopy (DBE) for HJS stricture at Nagoya University Hospital. We assessed the rate of reaching biliary anastomosis, procedure success rate, procedure duration, complications, improvement in liver function test results, and biliary anastomosis patency.In total, 19 ERC procedures with the use of DBE were performed for 9 adult LDLT recipients with HJS stricture from June 2006 to September 2014. Balloon dilation with the use of DBE was successfully performed in 5 of the 9 patients during the 1st procedure. Of the 4 patients in whom DBE-ERC failed to be completed, 3 patients underwent 2nd procedures successfully. Liver function test results were significantly improved in the successful cases. Four patients underwent 2nd DBE-ERC for stricture recurrence at a mean time of 2.3 years after the 1st successful procedure. Of those, 2 patients required 3rd procedures for stricture recurrence after the 2nd procedure.DBE-ERC is promising as a treatment for HJS stricture in adult LDLT recipients in the short term. However, the DBE-ERC procedure may have a considerable risk of restenosis.