Halide ion directed templation effect of quadruple-stranded helicates

• DOI: 10.1016/j.xcrp.2022.101056
• Publication Date: 2022-09-16T14:52:30Z
• Authors: Yang Liu; Zhiyuan Jiang; Yuming Guan; Qixia Bai; Zhe Zhang; Yiming Li; He Zhao; Ting-Zheng Xie; Ming Wang; Pingshan Wang; Tun Wu
• Keywords: 01 natural sciences; 0104 chemical sciences

The allosteric effect, described as biological enzymes' conformation change to accommodate specific substrates, plays an important role in metabolic regulation. However, well-organized aggregation of synthetic receptors into high-order supramolecular structures with different conformations and functions response a variety external stimuli presents formidable challenge. Herein, series quadruple-stranded helicates are created through the templation effect halide ions library metallo-macrocycles. Single-crystal X-ray diffraction unambiguously confirms that four intertwined strands bridged via eight robust C–H···X¯ hydrogen bonds, anion-π interactions, two electrostatic contacts. binding I¯ results D2-symmetric helicate, while Br¯ or Cl¯ adducts display asymmetric infrastructures. Furthermore, exhibits non-thermodynamically controlled, high selectivity toward due its nucleophilicity breaking up partial coordination bonds.