Racial differences in anxiety, depression, and quality of life in women with polycystic ovary syndrome

• DOI: 10.1016/j.xfre.2021.03.003
• Publication Date: 2021-03-14T07:48:50Z
• Authors: Snigdha Alur-Gupta; Iris Lee; Anat Chemerinski; Chang Liu; Jenna Lipson; Kelly Allison; Robert Gallop; Anuja Dokras
• Keywords: Depression

ObjectiveTo evaluate racial differences in the anxiety and depression prevalence scores women with polycystic ovary syndrome (PCOS).DesignCross-sectional.SettingAcademic institution.Patient(s)Reproductive-aged PCOS (n = 272) controls 295).Intervention(s)Hospital scale modified quality-of-life survey (MPCOS-Q).Main Outcome Measure(s)Differences score measured using hospital MPCOS-Q were determined between White Black PCOS. Multivariable correlation regressions assessed association of Ferriman-Gallwey score, total testosterone, body mass index (BMI), homeostatic model assessment insulin resistance anxiety, depression, scores.Result(s)Multivariable regression controlling for age, BMI, socioeconomic status showed that had a significantly higher than (75.9% vs. 61.3%) (mean ± SD, 10.3 4.1 8.7 4.6). The (24.4% 29%) (4.8 3.6 5.1 4.0) was not different. In multivariable regressions, interaction BMI race its significant. or models, although similar, infertility domain lower 12.6 7.8 17.5 6.8) indicating quality life related to infertility.ConclusionRacial identified domains suggest importance routine screening provide an opportunity targeted interventions based on race. To (PCOS). Cross-sectional. Academic institution. Reproductive-aged 295). Hospital (MPCOS-Q). Differences scores. infertility. Racial