Benefits of lumbar spine fusion surgery reach 10 years with various surgical indications

• DOI: 10.1016/j.xnsj.2023.100276
• Publication Date: 2023-09-09T22:28:25Z
• Authors: Leevi A. Toivonen; Arja Häkkinen; Liisa Pekkanen; Kati Kyrölä; Hannu Kautiainen; Marko H. Neva
• Keywords: Degenerative Disc Disease; Oswestry Disability Index; Back Pain

Lumbar spine fusion (LSF) surgery is a viable form of treatment for several spinal disorders. Treatment effects are preferably to be endorsed in real-life settings.This prospective study evaluated the 10-year outcomes LSF. A population-based series elective LSFs performed at 2 centers between January 2008 and June 2012 were enrolled. Surgeries tumor, acute fracture, or infection, neuromuscular scoliosis, postoperative conditions excluded. The following patient-reported outcome measures (PROMs) collected baseline, 1, 2, 5, 10 years postsurgery: VAS back leg pain, ODI, SF-36. Longitudinal PROMs analyzed using mixed-effects models.A total 683 patients met inclusion criteria, 630 (92%) them completed baseline least 1 follow-up PROMs, they constituted population. Mean age was 61 (SD 12) years, 69% women. According surgical indication, stratified into degenerative spondylolisthesis (DS, n=332, 53%), stenosis (SS, n=102, 16%), isthmic (IS, n=97, 15%), disc disease (DDD, n=52, 8%), deformity (DF, n=47, 7%).All diagnostic cohorts demonstrated significant improvement year, followed by partial loss benefits years. ODI baselines changes were: (DS) 45, -21, -14; (SS) 51, -24, -13; (IS) 41, -20; (DDD) 50, -20, (DF) -16, respectively. Comparable patterns seen pain scores. Significant HRQoL achievements recorded all cohorts, greatest physical domains, but also substantial mental aspects HRQoL.Benefits LSF partially lost still meaningful surgery. Long-term seemed milder with conditions, reflecting progress ongoing degeneration. Benefits most overt function measures.