The Xa7 resistance gene guards the rice susceptibility gene SWEET14 against exploitation by the bacterial blight pathogen

• DOI: 10.1016/j.xplc.2021.100164
• Publication Date: 2021-01-19T09:00:41Z
• Authors: Dangping Luo; Jose C. Huguet-Tapia; R. Taylor Raborn; Frank F. White; Volker P. Brendel; Bing Yang
• Keywords: Xanthomonas; R gene

Many plant disease resistance (R) genes function specifically in reaction to the presence of cognate effectors from a pathogen. Xanthomonas oryzae pathovar (Xoo) uses transcription activator-like (TALes) target specific rice for expression, thereby promoting host susceptibility bacterial blight. Here, we report molecular characterization Xa7, R gene TALes AvrXa7 and PthXo3, which major SWEET14. Xa7 was mapped unique 74-kb region. Gene expression analysis region revealed candidate that contained putative effector binding element (EBE) its promoter encoded 113-amino-acid peptide unknown function. Genome editing at locus rendered plants susceptible avrXa7-carrying Xoo strains. Both PthXo3 activated GUS reporter fused with EBE-containing Nicotiana benthamiana. The EBE is close mimic SWEET14 TALe-induced susceptibility. Ectopic triggers cell death N. prevalent indica accessions 3000 genomes. appears be an adaptation protects against pathogen exploitation