Characterization of antibiotic overuse for common infectious disease states at hospital discharge

• DOI: 10.1017/ash.2023.497
• Publication Date: 2023-12-12T07:28:28Z
• Authors: Rebecca Zodrow; Andrew Olson; Stephanie Willis; Dennis Grauer; Megan Klatt
• Keywords: Antimicrobial Stewardship

To evaluate rates of and outcomes associated with antibiotic overuse at hospital discharge for patients common infectious diseases states.Single-center, respective cohort study.A large, academic medical center in the Midwest United States.Adult who received antibiotics community-acquired pneumonia (CAP), uncomplicated cystitis, or mild, non-purulent cellulitis. Patients were excluded if they did not receive antibiotic(s) upon discharge, pregnant, severely immunocompromised, had concomitant infections, died during hospitalization, transferred to another an intensive care unit.Data abstracted from electronic record ambulatory orders included based on inpatient encounters August 1, 2021 through July 31, 2022.Of 182 study, was all three disease states: CAP (n = 87/125, 69.6%), cystitis 21/28, 75.0%), cellulitis 28/29, 96.6%). The prevailing reason excessive duration 127/182, 69.8%; mean 5.39 vs. 8.32 days, p 0.001). Antibiotic approximately one additional day (2.48 3.32 0.001), increase emergency department visits within 30 days after (1 0.001) compared without discharge.Antibiotic prevalent these states. Transitions should be prioritized as area antimicrobial stewardship intervention.