Supplementation of xanthophylls decreased proinflammatory and increased anti-inflammatory cytokines in hens and chicks

• DOI: 10.1017/s0007114512000025
• Publication Date: 2012-01-25T11:15:56Z
• Authors: Yu-Yun Gao; Qing-Mei Xie; Ling Jin; Bao-Li Sun; Jun Ji; Feng Chen; Jing-Yun Ma; Ying-Zuo Bi
• Keywords: Jejunum; Proinflammatory cytokine; In ovo

The present study investigated the effects of xanthophylls (containing 40 % lutein and 60 zeaxanthin) on proinflammatory cytokine (IL-1β, IL-6, interferon (IFN)-γ lipopolysaccharide-induced TNF-α factor (LITAF)) anti-inflammatory (IL-4 IL-10) expression breeding hens chicks. In Expt 1, a total 432 were fed diets supplemented with 0 (as control group), 20 or mg/kg (six replicates per treatment). liver, duodenum, jejunum ileum sampled at 35 d trial. results showed that both levels xanthophyll addition decreased IL-1β mRNA in liver jejunum, IL-6 IFN-γ LITAF compared to group. 2 was × factorial design. Male chicks hatched from diet containing either xanthophylls. collected 0, 7, 14 21 after hatching. ovo LITAF) increased mainly 0–7 gradually vanished dietary began work during 1–2 weeks Dietary modulated cytokines IFN-γ) (IL-10) onwards. conclusion, could regulate different tissues