An iodine balance study to explore the recommended nutrient intake of iodine in Chinese young adults

• DOI: 10.1017/s0007114520002196
• Publication Date: 2020-06-22T08:56:33Z
• Authors: Lichen Yang; Jun Wang; Jianjun Yang; Huidi Zhang; Xiaobing Liu; Deqian Mao; Jiaxi Lu; Yunyou Gu; Xiuwei Li; Haiyan Wang; Jing Xu; Hongxing Tan; Hongmin Zhang; Wei Yu; Xiujuan Tao; Yanna Fan; Qian Cai; Xiaoli Liu; Xiaoguang Yang
• Keywords: Adult; Male; 0301 basic medicine; 2. Zero hunger; China; Adolescent; Dose-Response Relationship, Drug; Nutritional Requirements; Fasting; Thyroid Function Tests; Healthy Volunteers; Diet; 3. Good health; Eating; Feces; Young Adult; 03 medical and health sciences; Sex Factors; Asian People; Humans; Female; Sodium Chloride, Dietary; Iodine

Abstract Data on average iodine requirements for the Chinese population are limited following implementation of long-term universal salt iodisation. We explored minimum young adults in China using a balance experiment and ‘iodine overflow’ hypothesis proposed by our team. Sixty healthy were enrolled to consume sequential experimental diet containing low, medium high levels (about 20, 40 60 μg/d, respectively). Each dose was consumed 4 d, daily intake, excretion retention assessed. All participants negative throughout study. Iodine differed among three ( P < 0·01 all groups). The zero-iodine derived from random effect model indicated mean intake 102 but poor correlation coefficients between observed predicted r 0·538 μg/d data) 0·304 data). As increased high, excreted (‘overflow’) through urine faeces males, 89·5 % females. Although level (63·4 μg/d) might be adequate corresponding 61·6 females did not meet optimal requirements. Our findings indicate that approximately half current recommended nutrient (120 may satisfy male China, while similar is insufficient based hypothesis.